Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #truncNotch_versus_absentNotch |
| Phenotype | phenotype_absentNotch_versus_truncNotch.cls#truncNotch_versus_absentNotch |
| Upregulated in class | absentNotch |
| GeneSet | BIOCARTA_ACTIONS OF NITRIC OXIDE IN THE HEART |
| Enrichment Score (ES) | -0.6567817 |
| Normalized Enrichment Score (NES) | -1.6089473 |
| Nominal p-value | 0.004140787 |
| FDR q-value | 0.23806562 |
| FWER p-Value | 0.896 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | TNNI1 | 3710040 | 1780 | 1.380 | -0.0391 | No | ||
| 2 | PDE2A | 6100504 | 2148 | 1.104 | -0.0134 | No | ||
| 3 | PDE3B | 2030563 | 2981 | 0.656 | -0.0312 | No | ||
| 4 | PRKG2 | 1110465 | 3300 | 0.538 | -0.0262 | No | ||
| 5 | NOS3 | 630152 670465 | 4423 | 0.280 | -0.0751 | No | ||
| 6 | HSP90AA1 | 4560041 5220133 2120722 | 5208 | 0.182 | -0.1098 | No | ||
| 7 | FLT1 | 3830167 4920438 | 5246 | 0.179 | -0.1044 | No | ||
| 8 | BDKRB2 | 4780706 | 5370 | 0.169 | -0.1041 | No | ||
| 9 | GUCY1B3 | 2970020 | 5608 | 0.152 | -0.1106 | No | ||
| 10 | GUCY1B2 | 2120128 | 6038 | 0.122 | -0.1287 | No | ||
| 11 | KNG1 | 6400576 6770347 | 6076 | 0.120 | -0.1258 | No | ||
| 12 | GNAQ | 430670 4210131 5900736 | 7189 | 0.072 | -0.1827 | No | ||
| 13 | GUCY1A2 | 1660441 | 8057 | 0.049 | -0.2273 | No | ||
| 14 | CAV1 | 870025 | 8401 | 0.041 | -0.2441 | No | ||
| 15 | CHRM1 | 4280619 | 8440 | 0.041 | -0.2445 | No | ||
| 16 | PIK3R1 | 4730671 | 8679 | 0.035 | -0.2558 | No | ||
| 17 | CAMK2B | 2760041 | 8961 | 0.030 | -0.2698 | No | ||
| 18 | KDR | 3610286 | 9378 | 0.022 | -0.2913 | No | ||
| 19 | RYR2 | 2760671 | 10167 | 0.008 | -0.3333 | No | ||
| 20 | PDE3A | 380068 | 10540 | 0.002 | -0.3533 | No | ||
| 21 | AKT1 | 5290746 | 11234 | -0.010 | -0.3902 | No | ||
| 22 | CHRNA1 | 1170025 3610364 5220292 | 11549 | -0.016 | -0.4064 | No | ||
| 23 | GUCY2F | 2450309 | 12187 | -0.029 | -0.4395 | No | ||
| 24 | PRKAR1B | 6130411 | 12273 | -0.030 | -0.4429 | No | ||
| 25 | PIK3CA | 6220129 | 12656 | -0.041 | -0.4618 | No | ||
| 26 | GNGT1 | 5220156 | 12765 | -0.044 | -0.4658 | No | ||
| 27 | FLT4 | 1240292 6350707 | 13518 | -0.072 | -0.5033 | No | ||
| 28 | GUCY1A3 | 110253 2640735 4070037 | 13634 | -0.078 | -0.5063 | No | ||
| 29 | PRKG1 | 4120671 | 13691 | -0.082 | -0.5060 | No | ||
| 30 | PLCG1 | 6020369 | 13938 | -0.098 | -0.5152 | No | ||
| 31 | SLC7A1 | 2450193 2710241 | 14336 | -0.137 | -0.5309 | No | ||
| 32 | GUCY2C | 110411 6110156 | 14868 | -0.228 | -0.5501 | No | ||
| 33 | PRKAR2B | 3130593 5220577 | 15901 | -0.577 | -0.5819 | Yes | ||
| 34 | PRKAR2A | 2340136 | 16096 | -0.664 | -0.5651 | Yes | ||
| 35 | PDPK1 | 6650168 | 17801 | -2.154 | -0.5682 | Yes | ||
| 36 | GNB1 | 2120397 | 17866 | -2.237 | -0.4797 | Yes | ||
| 37 | VEGFA | 2940338 | 18111 | -2.707 | -0.3815 | Yes | ||
| 38 | PRKAR1A | 3450369 | 18471 | -3.872 | -0.2416 | Yes | ||
| 39 | PRKACB | 4210170 | 18607 | -6.062 | 0.0005 | Yes |
